Zero people online can answer this as in order to use any air handling item, it needs to be suited to the size of the space that it is used in. If in a bedroom, you need to post the square ft/m of the bedroom and only use it there with the door shut. If your bedroom is open concept, you need to post the square ft/m of the entire space served.

3 fans is a bit nutty, find the right size one and buy it. Chuck the other ones. Again...they are based on room size.

But first, you should visit an allergist and find the solution to your problem rather than shooting in the dark.