I don’t think so. Every new step is a plateau.

I really think anti-matter or dark matter & discovering how to understand, and actually control or manipulate, the force of gravity are going to be HUGE difference makers.

True (not Hollywood or pedestrian) artificial intelligence and being able to truly create and design life will be similar game changers. Figuring out a concept of non-carbon based life will also be equally groundbreaking.

And finally the ability to continue the concept of “invisibility” fascinates me. I was deep in Popular Mechanics a long time ago and they were talking about the concept of invisibility - bending light waves around an object. It went from bending radio waves (ie radar invisibility), up to light waves (visual invisibility), and started talking about actual physical bending of things. Basically enabling physical things to not collide with each other. It was highly highly theoretical (like barely scientifically theoretical), but conceptually it makes you wonder how things will be 100 years from now, never mind 500 or another thousand.