I know what you're talking about. And you are right there is unknowns. But here is what we know.

1. Based on actual events (people messing up their brain with a fall, nail gun, or doctors cutting on the brain) you can forget things, act different, and even talk differently.
2. There has been cases where people hit there head (like dive in a pool that was too shallow) and while they lost a lot of abilities. With 0 training prior, they were a master of things like a piano.

You are talking about "you". Or more so the soul. But I'm talking about your hardware. Like we don't know enough and maybe it might make this impossible.

But lets assume I'm right and you could do most of this. Then in theory you could cure mental illnesses, change modern education to be more social and creative skills, and so on.