You're kind of right. For some reason when I read that passage, I thought of Berserk. It's not the only thing in fiction which explores that specific idea of incomprehensible loneliness and pain: there are many others, including One Hundred Years of Solitude, though in a very different way than the others, Kafka on the Shore, A Wizard of Earthsea... So many others.

But what they have in common is the rejection of a destiny, the contemplation of loneliness, the struggle of life, brought out in all of its forms.

Berserk, the manga, falls right into the middle of it. It's visceral, but it talks about struggling against a destiny of death. And that's life.