It's not necessarily true, but I think it's easy to get jaded when we hear a lot of emphasis on ATS. ATS is mostly used for light screening, and rarely used for "volume" screening. After all, employers want to find good candidates, and not unnecessarily screen people out. I have found that more people get cut out from not following the instructions than ATS.

Make sure that your resume is easy to parse. That means it should be text-based (word or PDF). I have a hard time with JPG and image-based resumes and it doesn't print very well. Make sure your resume has a single-column. The flashy "designer" resumes look cool, but if you're not in design or marketing, it might not screen through as well.

The winning resumes are concise. Word soup won't get very far.