Submitted by yeeturking t3_xx28my in askscience
CrateDane t1_irbbmet wrote
Reply to comment by Juls7243 in is it possible to synthesize proteins chemically? by yeeturking
> > > Mammalian Proteins are Glycosylated - this process is inherently heterogeneous. Most of proteins that are produced in humans and other mammals are covered with glycans (sugars) of varying length (1-20 monomer sugars).
Extracellular ones yes, but it's less common for cytoplasmic proteins.
On the other hand, you have a crapton of other modifications that are common on intracellular proteins. Phosphorylation, methylation, acetylation, acylations in general, SUMOylation, ubiquitination, neddylation, succinylation and so on and on.
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