Good question.

Well, cachexia is a wasting disorder, both muscles and fat are wasted,it increases insulin resistance, can also bring about increased platelet activation (thereby risking thromboembolitic events in future -> stroke-> death ) , can cause arrhythmias (leading to death). In short, Cachexia contributes to death. Obese individuals already have a higher risk for stroke, cachexia does only harm and no good.