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firstfrontiers t1_j50ntmt wrote

Reply to comment by Roadgoddess in Is there any difference in efficacy when a vaccine is administered somewhere other than the upper arm (e.g. on the foot)? by MercurioLeCher

There's overlap between medications and some medications can be given either way. However IM is going to be a slower release over time versus being immediately introduced all at once into the bloodstream. I know the form of medication or the substance it comes in plays a role too, some play better with different tissue types (some meds we give into the fat tissue as well depending on absorption). There's also the issue of bleeding risk which would be higher trying to give something IV when it's safer in a clinic setting to just give it IM. But as far as I'm aware the biggest factor is the more controlled release time

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Bax_Cadarn t1_j51914h wrote

You didn't mention one very important thing: research. To reguster a drug, You need data backing it up, either as safe and effective or noninferior to another similar drug(which is to say, it's not less afe and efficient).

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Indemnity4 t1_j530irm wrote

> noninferior to another similar drug(which is to say, it's not less afe and efficient).

A new drug can be inferior in some ways, provided it is better in others. For instance, if it is a lot cheaper, has fewer side effects, targets a sub-group not covered by the comparison or more easily made available.

For instance, medications suitable for pregnant women are often inferior (less effective) that comparisons.

Anyway, words are fun. You can make them mean whatever you want.

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