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SymmetryChaser t1_j78vtdx wrote

How does the data imply that methadone for pain is safer? The average (over dose size, which is a bad average as we don’t know how prevalent each dose is…) overdoses/100k of both groups are about the same, and for the same dose it seems like methadone for OUD is much much safer. The graphs do imply that large doses of methadone for OUD are less safe than small doses, but overall it seems like small and even moderate doses of methadone for OUD are much safer than the average use of methadone for pain.

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