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Solunette t1_iye0miz wrote

Insulin is a key that open the cells doors for sugar to enter and be used as fuel.

In insulin resistance the keyhole is blocked.

The body thinks there is a lack of keys because cells are screaming for fuel and it knows there is fuel. So it makes more insulin. This works for a time, basically forcing the locks.

But if not controlled even the excess insulin is not enough anymore.

The body is flooded with sugar it can't use and it ends up with diabetes.

As to why the keyholes get blocked... why does anything else go wrong in our bodies? Sometimes it's genetics, sometimes it's environmental, sometimes it's a combination of factors (like the change in hormones and the weight gain from pcos).

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TrigonSpawn OP t1_iye20ka wrote

Interesting. So we know the sugar being unable to be processed and building up in our body leads to diabetes, and the reason it can't be processed is due to the insulin resistance.

You mentioned that the body will try to provide additional insulin to attempt to "force the locks" in this example. Is there any impact from the excess insulin in our body? Or does it not build up the same way because it gets used (unfortunately unsuccessfully) when trying to process the sugar?

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Solunette t1_iye3fwe wrote

Insulin is an hormone. Any anormal hormonal level is bound to have consequences. Here it's called hyperinsulinemia if you want to read about it.

https://en.m.wikipedia.org/wiki/Hyperinsulinemia

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TrigonSpawn OP t1_iye3nkk wrote

....this is going to sound really stupid but never once have I ever actually realized wtf insulin is and that it, in fact, is a hormone.....welp my mind exploded just now.

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