Kinda sudden, but has your wife been evaluated for postpartum depression? If untreated, it can go on for a very long time, and thoughts of harming the children are one of the most common symptoms. I think the stress has gotten into her, and she did what she was able to do as a surgeon. Your wife needs psychiatric help with her psychosis and later with dealing with what she's done. As for the kids, some mothers suggest colloid silver and detox, they say it helps with any problem, cures autism, grows limbs etc. Maybe worth a try?