While I can understand your anxiety about this, I gotta tell ya, it's a man's world. Women aren't really safe no matter where we go, what we do, what we wear, what we say. That's just the facts. Yes, we can attempt to mitigate possible dangers but it's a crap shoot, either way. Like, for instance, she could correctly identify her Uber driver and he could assault her, as has happened many times. Cab drivers, cops, neighbors, boyfriends, husbands, fathers, uncles. Anyone with a penis is potentially dangerous. It's cute that you think she would be safe in her hotel room. Safer? Yeah, I guess. But we aren't even safe in our own homes. There is nowhere safe for us, unfortunately.

You can tell her you're concerned about her being inebriated in a foreign country and ask if she has a plan for transportation after the nightclub or whatever but honestly? It's your anxiety to deal with because she has her own constant low-level anxiety that she deals with every single minute of every single day. If she can deal with hers, you can deal with yours.