Oh I'm sorry to hear she also deals w fistulas! I had one and it was awful! I haven't found much that helps, I got into remission once for a couple years after a bowel resection but otherwise I've not had much luck. I did get to try Entyvio when it first came out but didn't have time to let it work before I needed surgery & there's some new drug out that also has great results in studies that I see a lot of people trying. I hope your wife gets a break from it all and gets a good remission. Take care of yourself too! It's hard to be on the sidelines watching!