shindleria t1_ir9o4sp wrote
Mt genes have been doing this for billions of years to become fully integrated into cellular signalling processes. Many of the mRNAs have 5’UTR sequences which confer unique trafficking and translation pathways, essentially a privileged form of molecular communication between the cell and mitochondria to control energy expenditure within the cell under a vast array of conditions. Some viruses have evolved to mimic these genetic properties to continue protein synthesis when the cell attempts to arrest translation. Truly fascinating.
knockonclouds t1_ircjkls wrote
Came here to say exactly this. Mitochondrial genes present in nuclear DNA is not new - it’s been there for a very long time people.
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