gauchocartero t1_isah59s wrote
Reply to comment by doveup in Scientists researching possible candidates for treating Alzheimer's disease found exercise outperformed all tested drugs for the ability to reverse dysregulated gene expression. by shadesofaltruism
Look at some of the proteins upregulated in the chart: YAP1, ITGB1, VASP, EZR, EGFR, RHOQ, NFKB, CDK2… All of these proteins are associated with increased tension in the cellular microenvironment as a result of abnormal matrix deposition, inflammation, oxidative stress.
doveup t1_isb6g3t wrote
True. And exercise is not 100% preventive. Nor is AD the only dementia. Still, there’s this study, charmingly titled for the season:
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