shiruken t1_j69s6bd wrote
Reply to comment by so2017 in COVID vaccines and first boosters provided protection to pregnant women during Omicron surge. Looking at unvaccinated women, you still have an increased death rate, and increased neonatal mortality. If you are vaccinated and boosted, especially with a mRNA vaccine, those levels drop by 81%. by Wagamaga
Correct, participants were enrolled from November 27, 2021 to June 30, 2022. The bivalent booster was not authorized until August 31, 2022.
That being said, vaccination was still highly effective at preventing several maternal complications and outcomes:
>Reassuringly, the vaccine effectiveness of all vaccines combined to prevent severe maternal morbidity and referral, ICU admission, or death was 76% amongst all women given a booster dose. The respective vaccine effectiveness values for mRNA vaccines with a booster dose was 81%. For women with a diagnosis, vaccine effectiveness for the same outcomes, of all vaccines combined, was 74% (95% CI 48–87) for the complete regimen and 91% (65–98) after a booster dose.
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