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thewildsilence t1_iw2nwj4 wrote

Reply to comment by fuckpudding in Shape of a protein predicted by two different AI models (ESMFold on the left, AlphaFold on the right) by greentea387

Seems to me that they’re such small changes, they would be part of the normal dynamics of the protein at room temperature. So they could very easily interconvert. If that’s indeed the case they’re essentially the same thing.

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autouzi t1_iw3ypb1 wrote

This may or may not be always true, so a good scientist would not make that assumption unless they didn't have a choice.

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iyke7991 t1_iw6fxv7 wrote

He's discussing possibilities. No concrete or final assumptions being made. A "good scientist" leaves all possibilities open. Not like it matters here, we're not the researchers, just nerds discussing.

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