I agree but I also think we are on the threshold of a time of rapid scientific advancement. As an example, we’ve known about protein folding and gene function for decades so advances driven by AlphaFold or CRISPR may not qualify as disruptive discoveries but they will lead to revolutionary changes in our approach to medicine and our understanding of underlying biology. That same process is happening across multiple fields where the foundational science is understood but rapid technological advances are transforming the way that knowledge is used.