My former co-worker quit to teach diving and run boat tours in the Caribbean.

Several yoga teachers at my old studio had gone from enthusiastic practitioners with office jobs to part time instructors to full time instructors.

My friend left corporate law when she had kids and never looked back (husband has a good job and she loathed big law). She may go back part time but won't be pursuing anything in the legal field.

Not sure this counts because it's actually more work, but my other friend quit Big 4 consulting to go to medical school to be a pediatrician.