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8 results for aacrjournals.org:
budrose13 t1_izueh6s wrote
Reply to If genetic mutations are random, why are some (nonhereditary) mutations so common while others are rare? by animalgames
years of our understanding of cancer genetics and molecular mechanisms. https://www.cell.com/fulltext/S0092-8674(00)81683-9 https://www.cell.com/fulltext/S0092-8674(11)00127-9 https://aacrjournals.org/cancerdiscovery/article/12/1/31/675608/Hallmarks-of-Cancer-New-DimensionsHallmarks-of
Rain_Dont_Pour OP t1_jb50wox wrote
Reply to Interesting relationship between Chemoresistant Ovarian Cancer and Follistatin. Follistatin production increased chemoresistance by communicating with neighboring cells to promote quiescence. Could be a potential target for therapy in the most deadly gynecological cancer. by Rain_Dont_Pour
aacrjournals.org/clincancerres/article-abstract/doi/10.1158/1078-0432.CCR-22-2254/716616/Quiescent-ovarian-cancer-cells-secrete-follistatin?redirectedFrom=fulltext](https://aacrjournals.org/clincancerres/article-abstract/doi/10.1158/1078-0432.CCR-22-2254/716616/Quiescent-ovarian-cancer-cells-secrete-follistatin?redirectedFrom=fulltext) DOI: https://doi.org/10.1158/1078-0432.CCR-22-2254
chrisdh79 OP t1_jbesegd wrote
Reply to Two-pronged immunotherapy eliminates metastatic breast cancer in mice | Suggests a new approach for treating breast cancers that have spread to bone by chrisdh79
bones of mice, and continued to eliminate tumor cells that eventually returned. The [study](https://aacrjournals.org/cancerdiscovery/article-abstract/doi/10.1158/2159-8290.CD-22-0907/716615/p38MAPKa-stromal-reprogramming-sensitizes?redirectedFrom=fulltext) is published March 8 in Cancer Discovery, a journal of the American Association for Cancer Research. Macrophages
adamredwoods t1_jbig6xq wrote
Reply to Two-pronged immunotherapy eliminates metastatic breast cancer in mice | Suggests a new approach for treating breast cancers that have spread to bone by chrisdh79
that's a good sign. Not sure what's stopping them from starting? Actual paper: [https://aacrjournals.org/cancerdiscovery/article-abstract/doi/10.1158/2159-8290.CD-22-0907/716615/p38MAPKa-stromal-reprogramming-sensitizes](https://aacrjournals.org/cancerdiscovery/article-abstract/doi/10.1158/2159-8290.CD-22-0907/716615/p38MAPKa-stromal-reprogramming-sensitizes) Associated links: [https://www.mycancergenome.org/content/drugs/tavolimab/](https://www.mycancergenome.org/content/drugs/tavolimab/) [https://en.wikipedia.org/wiki/P38\_mitogen-activated\_protein\_kinases](https://en.wikipedia.org/wiki/P38_mitogen-activated_protein_kinases) [https://pubmed.ncbi.nlm.nih.gov
unswsydney OP t1_jc5iic1 wrote
Reply to Cancer researchers show introducing bacteria to a tumour’s microenvironment creates a state of acute inflammation that triggers the immune system’s primary responder cells to attack rather than protect a tumour. by unswsydney
work has been published in the journal Cancer Research, and is available to read here: https://aacrjournals.org/cancerres/article/doi/10.1158/0008-5472.CAN-21-4025/716558/Neutrophil-conversion-to-a-tumor-killing-phenotype
bdesign7 t1_iuhxjwz wrote
Reply to comment by Rc72 in TIL that chemotherapy can be traced back to the sinking of an Allied ship secretly carrying chemical weapons in WW2 by Rc72
aacrjournals.org/cancerres/article/68/21/8643/541799/A-History-of-Cancer-Chemotherapy#12307971 Nope, they’re correct