>A cross-linkage analysis of more than 90,000 deliveries has found that women with a history of PCOS were at a higher risk of gestational diabetes, pre-eclampsia and Caesarean section than those without PCOS; extra monitoring is advised for PCOS pregnancies.
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>A prodigious cross-linkage registry study from the USA has confirmed what many smaller studies have previously found, that pregnant women with polycystic ovary syndrome are at increased risk of gestational diabetes, hypertensive disorders of pregnancy and delivery by Caesarean section.(1) Moreover, the infants born to PCOS women were found at increased risk of low birthweight, small for gestational age, preterm birth, prolonged neonatal hospital stay and infectious and respiratory conditions within the first year of life.
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>The risks of such pregnancy complications were found sufficiently high for the authors to advise that ‘obstetricians should be aware of patients’ PCOS status and closely monitor for potential pregnancy complications to improve maternal and infant perinatal health outcomes’. Adjusted relative risks for gestational diabetes were 1.51 (1.38-1.65), for pregnancy induced hypertension 1.25 (1.15-1.35) and Cesarean section 1.07 (1.02-1.11). The association between PCOS and gestational diabetes was strongest in women with a pre-pregnancy BMI of <30 kg/m2. The authors’ warning echoes that of the 2018 international guidelines on PCOS, which similarly recommended increased monitoring for women with PCOS during pregnancy.(2)
CognitiveFunction34 OP t1_ismjcnh wrote
Reply to Large population study reaffirms link between PCOS and metabolic complications of pregnancy by CognitiveFunction34
>A cross-linkage analysis of more than 90,000 deliveries has found that women with a history of PCOS were at a higher risk of gestational diabetes, pre-eclampsia and Caesarean section than those without PCOS; extra monitoring is advised for PCOS pregnancies.
>
>A prodigious cross-linkage registry study from the USA has confirmed what many smaller studies have previously found, that pregnant women with polycystic ovary syndrome are at increased risk of gestational diabetes, hypertensive disorders of pregnancy and delivery by Caesarean section.(1) Moreover, the infants born to PCOS women were found at increased risk of low birthweight, small for gestational age, preterm birth, prolonged neonatal hospital stay and infectious and respiratory conditions within the first year of life.
>
>The risks of such pregnancy complications were found sufficiently high for the authors to advise that ‘obstetricians should be aware of patients’ PCOS status and closely monitor for potential pregnancy complications to improve maternal and infant perinatal health outcomes’. Adjusted relative risks for gestational diabetes were 1.51 (1.38-1.65), for pregnancy induced hypertension 1.25 (1.15-1.35) and Cesarean section 1.07 (1.02-1.11). The association between PCOS and gestational diabetes was strongest in women with a pre-pregnancy BMI of <30 kg/m2. The authors’ warning echoes that of the 2018 international guidelines on PCOS, which similarly recommended increased monitoring for women with PCOS during pregnancy.(2)