DurianBig3503

DurianBig3503 t1_jb5qbjp wrote on March 6, 2023 at 5:11 PM

Reply to comment by Shark-Whisperer in Why don't researchers just use conjugated primary antibodies for ELISAs? by ursoda

Moreover, price. If you want a new target you dont have to make a whole batch of new signalling AB just the primary AB of the same origin as before so they too can be targeted by the secondary AB.

DurianBig3503 t1_ja8q9ko wrote on February 27, 2023 at 5:58 PM

Reply to Is there a genetic disease where the heterozygote has more severe disease symptoms than the homozygote? by Altranite-

Theoretically, if;

Both alleles are transcriptionally active.
It forms a homopolymer.
Both forms are functional.

Then it could happen that either homozygote functions better than the heterozygote. I have never seen it.