Jrj84105
Jrj84105 t1_ja8gski wrote
Reply to comment by iayork in Is there a genetic disease where the heterozygote has more severe disease symptoms than the homozygote? by Altranite-
This is region so highly conserved. The imprinting of genes on both the maternal and paternal alleles makes any genetic chaos here quite deleterious.
Jrj84105 t1_j8pyvgw wrote
Reply to comment by Procrasturbating in TIL that Martha's Vineyard constitutes the County of Dukes County. This redundant name is due to the fact that it was formed as Dukes County in New York before being transferred to Massachusetts and reincorporated under its current name in 1695. by nxdat
That tracks. My line was wealthy and very prominent until the Yankee-Pennamite War. Charles II deeded the Susquehanna river region- the Wyoming Valley- to both New York and Willam Penn.
My ancestors were imprisoned and all their property taken by the Pennamites. They were left homeless and penniless an had the life skills of essentially being rich people.
Generations later they were still blaming their misfortune on “those damn Pennamite bastards”. They basically Forzt Gumped their way through American history from Martha’s Vineyard to the Sutter’s Mill being tangential side characters in lots of American history.
Jrj84105 t1_j8ll5s5 wrote
Reply to TIL that Martha's Vineyard constitutes the County of Dukes County. This redundant name is due to the fact that it was formed as Dukes County in New York before being transferred to Massachusetts and reincorporated under its current name in 1695. by nxdat
Martha was my 13th great grandmother. TIL somehow also Taylor Swift’s 7th great grandmother. Don’t know how she has so many fewer generations in there.
Jrj84105 t1_jacnuvz wrote
Reply to Researchers have developed a new device that can detect and analyse cancer cells from blood samples, enabling doctors to avoid invasive biopsy surgeries, and to monitor treatment progress by giuliomagnifico
Blood is basically an organ in and of itself.
Liquid biopsies and circulating tumor cell analysis isn’t a novel technology. The problem is that blood is just one of many places metastases may go, so it tends to be less informative than hoped.