Sariel007

Sariel007 OP t1_ivti616 wrote

>LG Disply has developed a 12-inch stretchable display that can be extended in size to 14 inches, the company announced. The displays could one day be used in materials with irregular surfaces like clothes and wearables to display messages on the uniforms of first responders, for example.

>Stretchable displays, or free-form displays as LG Display calls them, can be pulled, bent and twisted. They go a step farther than the flexible displays used in Samsung's Galaxy Fold and other smartphones, which can be folded and bent but not stretched.

>To make the display so stretchy, LG Display built the base substrate material from a silicon similar to that used in contact lenses. It also micro-LEDs smaller than 40-micrometers for the light source, allowing for high resolution and durability. And finally, the company used circuits shaped like springs to accommodate bending and folding.

11

Sariel007 OP t1_iva82f9 wrote

>Deep-sea exploration has long been largely a privilege of billionaires, fossil fuel companies, and a select few scientists from wealthy nations. This exclusivity has left the vast majority of the deep sea unexplored, its natural wonders understudied and vulnerable to exploitation. In recent years, scientists and conservationists have called for the democratization of the deep sea. They say this extreme region of the planet needs to be accessible to everyone. Now, a group of scientists, conservationists, and explorers has devised a low-cost device that is helping bring that goal closer to reality.

>Called the Maka Niu, which means “coconut eye” in Hawaiian, the device was initially created by scientists at the Massachusetts Institute of Technology (MIT) and is now being developed by the nonprofit Ocean Discovery League. Looking like little more than a piece of PVC pipe stuffed with gadgets, the compact, customizable, and relatively inexpensive battery-powered data collector can capture video and measure depth, temperature, and salinity at depths as great as 1,500 meters. That’s about five times deeper than even the most specially trained scuba diver can go and deep enough to reach the ocean’s midnight zone, home to deep-sea animals like the vampire squid and chambered nautilus.

>A newer version of the Maka Niu can go even deeper says Katy Croff Bell, the deep-sea explorer, scientist, founder of the Ocean Discovery League, and leader of the MIT team. “We have designs that can go to 6,000 meters, which would enable it to reach 99 percent of the seafloor,” she says.

9

Sariel007 OP t1_itgodrs wrote

>Cellular repopulation has been used for years, a process that injects healthy liver cells into the patient’s damaged organ through a portal vein where they adhere themselves to the existing cellular scaffolding and grow into new, functional liver tissue.

>Creating an immediately available and inexhaustible supply of functioning liver cells from autologous tissue would allow early intervention in patients with hepatic failure and would allow liver cells to be infused over a longer period of time,” the 2016 study’s authors note. “Combined with recent advances in genome-editing technology, such liver cells could be used widely to treat devastating liver-based inborn errors of metabolism and to eliminate the need for a life-long regimen of immunosuppressive drugs and their complications.” The downside to this technique is the pace at which the donor cells proliferate, making it a poor tool against acute liver failure.

>Extracellular Vesicle-based therapies, on the other hand, leverage the body’s intracellular communications pathways to deliver drugs with, “high bioavailability, exceptional biocompatibility, and low immunogenicity,” according to 2020’s Extracellular Vesicle-Based Therapeutics: Preclinical and Clinical Investigations. “They provide a means for intercellular communication and the transmission of bioactive compounds to targeted tissues, cells, and organs” including “fibroblasts, neuronal cells, macrophages, and even cancer cells.”

>EVs are the postal letters that cells send one another. They come in a variety of sizes from 30 to 1000 nm and have exterior membranes studded with multiple adhesive proteins that grant them entry into any number of different types of cells. Exploiting the biological equivalent to a janitor’s key ring, researchers have begun tucking therapeutic nanoparticles into EVs and using them to discreetly inject treatments into the targeted cells. However, these treatments are still in the experimental stages and are most effective against acute liver failure and inborn metabolic diseases rather than end-stage liver failure.

10