For the sake of argument, I will agree with the premise that we have a drive to make a difference.

However, my point still stands. Every individual will make the determination of what a "positive difference" means. It could be picking up trash in a local forest. It could be raising your kids well. It could be teaching everyone that the true meaning of the [name of religious text] is that we should kill the [insert enemy]."

I think the hard wiring is to preserve your genetics. The next most common drive is to preserve memetics.

There is still no objective measure of "genetic preservation". You can have children. You can protect your brothers children in an act of altruism [save them from a fire that kills you]. You can try to preserve "your race." People think of all kinds of wacky things...

There is no meaning to life other than what you have invented for it. If you can invent meaning for yourself in non-AI today, you will invent meaning in post-AI tomorrow.

If you don't need meaning today; then you won't tomorrow.