Thank you China and Purdue Pharmaceutical/The Sackler family.

https://www.dea.gov/sites/default/files/2020-03/DEA_GOV_DIR-008-20%20Fentanyl%20Flow%20in%20the%20United%20States_0.pdf

Dammit! lol. Thanks.

Who are the “pricks with ears” in the Greek version.

Bill Haley fucked this all up.

File this under, “You're All Fucked!”

Thanks for all the Hawaiian Punch and Coca-Cola mom!

You're missing the point. The commenters are omniscient.

Yes, it's one of the 5 boroughs of New York City. I think they were just focusing on that borough because it puts it in a higher population density bracket when compared with the other boroughs, which are less dense.

The hardest thing to overcome with exercise research is the lack of a placebo control. i like that they showed dcreases in inflammatory markers in this study.

I worked in a psych hospital for a few years in the early 1990s, on a locked unit. It was a private hospital and about as nice as one could hope for. So it wasn't an underfunded state hospital. In retrospect, I just realized that they had zero opportunities for patients to exercise. There was a courtyard for getting fresh air, but it was too small to do any walking. So not only were there no opportunities (any kind of a gym, place for walking/running), the unit did not even physically allow for exercise in those who would want to.

So funny to see the reactions of the rich people when they arrive and see the shitty tents they're supposed to sleep in.

It's from an 8th century Indian Buddhist philosopher named Shantideva. See No Time to Lose by Pema Chodron if interested.

You can cover the world with leather or you can put shoes on.

They're making a reference to the Game of Thrones' character also named John Snow.

His watch has ended.

That's a common issue with self-esteem training, a prominent downside.

Self-Compassion by Kristin Neff is an excellent antidote to this.

Books that are about more well-rounded development of character strengths and virtues (positive psychology) tend to be better. There's some thought towards altruism, the greater good, feeling like part of something greater (secular or religious), etc. Self-esteem books are narrow in scope.

They also played air guitar on the paddles

But they also get more Alzheimers's, more depression, less aphasia from stroke, less dyslexia, and less impulsivity (all of these are on average in large samples.

How to Doubly Fúck the Planet

Natural environments reduce emotional distress. Chronic stress increases inflammation, and the risk of neurodegenerative diseases.

https://www.sciencedirect.com/science/article/pii/S2352289518300079

Also chronic stress and inflammation. Many dementias seem to have an inflammation component to the neurodegeneration.

it’s exposure to pollution. At least one study controlled for socioeconomic status and showed the relationship persisted.

That poor kid was drunk and doing coke by age 12. Went to rehab at 13.

Makes me wonder whether a low glycemic index/load diet plus supplement with exogenous ketones would be preventative.

Ketones as well.

Yes, so this seems like at least one plausible mechanism.

In principle, a ketogenic diet keeps insulin levels steady and low, minimizing insulin resistance. People do ingest some carbohydrate (low glycemic load) and the body does produce some glucose via gluconeogenesis.