jawshoeaw

jawshoeaw t1_ixnih11 wrote

I wouldn’t think so but it’s a valid concern. Your immune system is already primed to attack any of the gut bacteria should they escape (and in fact they do regularly escape and are killed constantly). Also the interior of the gut is somewhat of an immunologically protected zone , I think of it as outside the body.

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jawshoeaw t1_iw72gv3 wrote

Warfarin is in a sense a vitamin k poison. However, when you eat vitamin k containing foods such as leafy green vegetables, it has zero effect on the metabolism of warfarin. Instead the vitamin K acts as an antidote by replacing the vitamin K that warfarin blocked. There are other drugs that can affect the metabolism of warfarin however.

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jawshoeaw t1_ismjz4x wrote

I have seen strep throat turn into life threatening and even fatal necrotizing infections. However, most of the time you don’t have an active population of strep pyogenes bacteria in your mouth. Only 1-2% of people carry it in their mouths. Also the cuts and scrapes are usually very shallow and your mouth is lined with immune cells waiting to attack anything that might try to break through. As you might guess places like your mouth and your anus have a significant immune presence .

Necrotizing fasciitis is interestingly rare even with serious strep infections. It’s not as simple as strep or other bacteria causing an infection, other complex factors are at play. Most cases are in people with poor immune function, diabetes,’ drug use , malnutrition, or some combination of these. One theory is that the bacteria communicate with one another and send a signal saying basically to go full on attack mode.

Tl:dr strep a is rare to start with, and even if you get a strep infection, NF is still rare. A cut or scrape is usually shallow enough that bacteria can’t get very far and your immune system has a strong presence in the mouth

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jawshoeaw t1_ismhi6t wrote

I don’t think that first part is completely correct . Bacteria that stumble into the blood stream are often destroyed immediately via the complement system and then somewhat unexpectedly by red blood cells . The chance a white blood cell would randomly bump into a free floating bacterium is fairly low. If you have a large number of bacteria in your blood stream your immune system has failed significantly in containment and can be life threatening as there is no way for the host to mount a vigorous immune response within the vascular system itself and within seconds the bacteria can find their way to distant targets normally impossible for them to reach. I guess I only see the people where this system has failed so maybe I’m biased , but we see bacteremic patients all the time. Often immunocompromised and/or with poorly controlled diabetes. They may have septic emboli into the lungs , liver brain, spleen, spine , and for some reason the psoas muscle is a popular landing spot. But the blood steam is almost alway quickly cleansed of bacteria once antibiotics are started even tho primary infection is still active. Blood is a hostile environment

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jawshoeaw t1_iskblhi wrote

We have almost no homology with lettuce. 10-15 % of coding DNA maybe . If you cherry pick (lettuce pick ?) certain genes common to all life on earth , then unsurprisingly we have 99% similar genes. But what about the lettuce genes for the spine? Or blood cells? There’s no way to compare because plants lack these genes completely.

And comparing to chimps even is misleading. Which genes are you comparing? Do they have to be 100% the same to count as 100% homologous? Any two cells in my body might be off .1% which changes count? One paper I read said we are only 18% homologous to chimps

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jawshoeaw t1_iqyq0tf wrote

I did some rough calculations of how much energy the DART craft had and it was about 1/1000 of the atomic bomb over Hiroshima. 1/1000 doesn’t sound like much but this was just an initial try. And that’s still equivalent to 15 tons of TNT. Not bad. The problem with a nuke is you can’t just slam it in, you first have to slow down, match speeds , then land and tunnel into the middle of it . Maybe all doable but dang .

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